Rewiring the Future: ETSU maps circuits that may curb autonomic dysreflexia

ETSU researchers led by Matthew Zahner say they are using chemogenetics and viral microinjections to map circuits that control autonomic function after spinal cord injury and report that targeted locus coeruleus stimulation can inhibit stress responses and lower blood pressure, according to an ETSU profile.

Read more

Conference urges nerve‑centric view of endometriosis and flags vagus‑nerve approaches

At this year’s Endometriosis Foundation of America conference, clinicians pushed a nerve‑centric model for endometriosis pain and spotlighted the vagus nerve and vagus‑nerve stimulation as potential therapeutic avenues, while urging better presurgical mapping and complete excision.

Read more

Parkinson's patient shows improvement after DBS at KGMU

A 50-year-old Parkinson's patient with a nearly 25-year disease history showed clinical improvement after deep brain stimulation at King George's Medical University on March 25; the surgery involved KGMU neurosurgeons and visiting experts from NIMHANS.

Read more

Former Bloomfield Hills teacher regains function after deep brain stimulation for essential tremor

Retired Bloomfield Hills teacher Mark Honeyman had his three‑year‑old deep brain stimulation implant replaced at Henry Ford Health after receiving DBS for essential tremor in 2022. The surgery and replacement restored daily function and inspired a short documentary, "Still Honeyman."

Read more

Technical description outlines ultrasound-guided bilateral hydrodissection of cervical sympathetic chain and vagus nerves

A new technical description lays out an ultrasound-guided, bilateral simultaneous hydrodissection technique targeting the cervical sympathetic chain and vagus nerves, with anatomical mapping and stepwise sonographic guidance. The report is procedural and does not include clinical outcomes.

Read more

Randomized head-to-head TMS trial: medial prefrontal target produced larger anxiety drops than conventional DLPFC in comorbid depression

A phase 2 randomized trial (NCT04604210) found neuronavigated TMS to a dorsomedial prefrontal cortex target reduced anxiety more than a conventional left DLPFC target in patients with major depressive disorder and comorbid anxiety; both targets produced similar depression improvements.

Read more

Duke-led simulations show skull‑conforming flexible ultrasound arrays sharpen subcortical tFUS targeting

A Duke University simulation study (npj Acoustics, 30 Mar 2026) finds skull‑conforming flexible ultrasound arrays can produce smaller foci, higher peak pressure and lower sidelobes than a semi‑spherical array for ~4 cm subcortical targets; results come from MRI‑derived head models and are computational only.

Read more

Lantern-shaped ventricular BCI records stable deep-brain signals and decodes rat memory with 98% accuracy

A Tsinghua University team placed an expandable, lantern‑shaped electrode inside the lateral ventricle. In rats the ventricular BCI recorded stable signals for up to six months and decoded memory‑guided T‑maze choices with up to 98% accuracy.

Read more

Cortical beta rhythms encode motor and uncertainty signals; beta‑frequency rTMS shortens reaction time

A 2026 EEG‑rTMS study in 24 adults shows cortical beta oscillations separately encode uncertainty and movement preparation, and that beta‑frequency rTMS—especially when started at the beta trough—shortens reaction times and reduces beta desynchronisation.

Read more

Evidence-based decision tool for deep brain stimulation found acceptable by Parkinson’s patients

Neurology researchers published an evidence-based decision tool for deep brain stimulation on Mar 27, 2026; Parkinson’s patients in the report found the tool acceptable and rated its quality positively. The announcement did not include sample size or detailed outcome metrics and called for further evaluation.

Read more

Texas A&M builds digital human to detect early dementia through apathy screening

Texas A&M researchers are developing an AI "digital human" that asks screening questions and analyzes facial expressions and biometrics to generate a "Digital Apathy Signature" aimed at improving early dementia detection.

Read more

Columbia researcher wins grant to test rTMS on brain circuit linked to restrictive eating

Columbia psychologist Alexandra Muratore received the GFED Young Investigator Award to fund rTMS studies probing a brain circuit linked to restrictive eating in anorexia nervosa. The project will test whether non‑invasive magnetic stimulation changes symptoms and could inform mechanism‑based treatments.

Read more

Polydopamine-doped PEDOT coatings lower electrode impedance and strengthen cell–electrode contact

Sharif University researchers report a polydopamine-doped PEDOT coating that cuts 1 kHz impedance to ~270 Ω, makes the surface superhydrophilic, and increases cell adhesion in vitro; molecular dynamics show stronger membrane binding for PDA-containing interfaces.

Read more

Neurovascular impulse response function reflects region-specific neuromodulation across mouse cortex

Boston University researchers show that the neurovascular impulse response linking neural activity to blood volume varies across cortical regions in mice and reflects local neuromodulatory signals; data and code are publicly available on DANDI and GitHub.

Read more

USC-led ENIGMA study finds contralesional 'youthful' brain patterns linked to severe motor impairment after stroke

A multicohort ENIGMA study published in The Lancet Digital Health finds that large strokes speed aging in damaged tissue while making contralesional frontoparietal regions appear younger; the pattern correlates with severe, persistent motor deficits and may reflect compensatory neuroplasticity.

Read more

Mouse study links early‑adult stress‑drinking to locus coeruleus dysfunction and midlife cognitive decline

A mouse study in Alcohol Clinical & Experimental Research finds that drinking to cope with stress in early adulthood produced lasting locus coeruleus dysfunction, higher oxidative stress, and midlife cognitive deficits in mice; human implications remain unproven.

Read more