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Secondary head-to-head comparison: LIFU vs rTMS for motor recovery after stroke

A PLOS One secondary analysis of a randomized trial (n=50) found similar short‑term Fugl–Meyer and Barthel gains after subacute stroke with LIFU or rTMS, while LIFU produced larger change‑from‑baseline motor improvements and increased prefrontal fALFF on fNIRS.

25 Apr 2026

Review details mechanisms, clinical uses and limits of tACS across neuropsychiatric disorders

A review led by Prof. Hongxing Wang (Chinese Medical Journal, 5 Apr 2026) summarizes proposed mechanisms and reported clinical uses of tACS across depression, Alzheimer's, schizophrenia and stroke, and calls for larger randomized trials and closed-loop protocols.

23 Apr 2026

Nature Reviews Bioengineering publishes framework for digital biomarkers in neurodegenerative disease

A Stanford-led review published 23 April 2026 in Nature Reviews Bioengineering presents a three‑pillar framework for digital biomarkers in neurodegenerative disease, highlights mature motor measures (like gait via IMUs) and lists gaps: small studies, interoperability, equity and cost-effectiveness.

23 Apr 2026

Chaotic heartbeat patterns track cognitive brain activity better than conventional HRV, Kyoto researchers report

Kyoto University researchers found that chaos-based measures of heart-rate variability change with cognitive task load while conventional HRV does not, suggesting a noninvasive signal of brain–heart coupling (Scientific Reports, 2026).

23 Apr 2026

SCRATCH‑HTN pilot: ear‑based neuromodulation safe but misses primary endpoint; 12 mmHg signal in highest‑BP subgroup

At ACC 2026, investigators reported SCRATCH‑HTN pilot results: transcutaneous autonomic neuromodulation was safe and acceptable but did not beat sham overall; a subgroup with higher baseline systolic blood pressure showed about a 12 mmHg reduction. The randomized pilot enrolled 63 patients (2:1 randomization).

22 Apr 2026

Northwestern team prints artificial neurons that activate living mouse brain cells

Northwestern researchers printed flexible electronic neurons from MoS2 and graphene that generated complex spike patterns and activated neurons in mouse cerebellum slices, the team reports in Nature Nanotechnology. The paper frames the result as a step toward direct brain–device communication and more energy-efficient neuromorphic hardware.

22 Apr 2026

Japanese team launches open‑label pilot of Vielight PBM for cognitive impairment in schizophrenia

NCNP Tokyo has started a single‑arm 12‑week pilot trial of combined transcranial and intranasal photobiomodulation using the Vielight Neuro Gamma 4 in people with schizophrenia. The study (jRCTs032240756) will prioritize safety and tolerability and explore effects on cognition (MCCB), MMN and frontal NIRS.

22 Apr 2026

Review: Neuromodulation techniques relieve IBS symptoms, long-term benefit uncertain

A 21 April 2026 Frontiers review by Zhang et al. finds electroacupuncture, sacral nerve stimulation, taVNS and TENS can improve IBS symptoms but notes large patient-to-patient variability and limited long-term data.

22 Apr 2026

MRI-guided TMS reduces amygdala threat responses and improves PTSD symptoms

A randomized, blinded Emory trial found two weeks of MRI-guided low-frequency TMS reduced right amygdala threat responses and produced clinically meaningful PTSD symptom relief in 74% of treated participants, with benefits lasting at least six months.

21 Apr 2026

Pulsed taVNS elicits pupil dilation only with earlobe sham and short pulses, study finds

A Psychophysiology study (Apr 2026) finds pulsed taVNS produces pupil dilation in intermixed trials only with short (1.0 s) pulses and an earlobe sham; using a scapha sham or timing pulses to exhalation removed the effect, challenging a vagal-afferent mechanism.

21 Apr 2026

Tomsk Polytechnic University develops magnetoelectric nanoparticles for non‑invasive brain stimulation

Tomsk Polytechnic University researchers report sub‑30 nm magnetoelectric nanoparticles (manganese ferrite core, barium titanate shell) that, in lab tests, tripled neuronal calcium influx and activated 20% more cells; the team says particles are biocompatible at therapeutic concentrations and that in vivo studies are next.

20 Apr 2026

Year-long aerobic exercise cut long-term cortisol in randomized trial, but most heart‑and‑brain markers were unchanged

A randomized year-long trial of 130 adults found 150 minutes/week of aerobic exercise reduced hair cortisol, a multi-month marker of systemic stress, while cholesterol, inflammation, vascular measures and MRI stress responses showed no clear change.

19 Apr 2026

Implantable BCI enables rapid typing for two people with paralysis

Mass General Brigham and Brown researchers report an implantable intracortical BCI that let two BrainGate trial participants—one with ALS and one with a cervical spinal cord injury—type up to ~22 words per minute with a 1.6% word error rate after brief calibration.

18 Apr 2026

Israeli team shows low‑frequency DBS of globus pallidus externus reverses schizophrenia‑like inflexibility in monkeys

A study published in Nature Communications shows 13 Hz deep brain stimulation of the globus pallidus externus improved error‑driven behavioral flexibility in two monkeys with PCP‑induced schizophrenia‑like deficits. The work identifies a basal‑ganglia circuit linked to a core symptom but is limited to a small animal model.

18 Apr 2026

UC Irvine-led team demonstrates brain-controlled exoskeleton walking with direct cortical leg sensation

A UC Irvine-led team reported a bidirectional brain-computer interface that allowed a participant to control an Ekso GT exoskeleton and perceive artificial leg sensations via direct cortical stimulation, with step-count accuracy near 93%. The prototype runs on a compact embedded platform and the authors describe a path toward fully implantable systems.

18 Apr 2026

Study reveals how bacteria 'selflessly' share DNA through GTAs

A new study provides fresh insight into gene transfer agents (GTAs), virus-like particles bacteria use to move DNA between cells, and clarifies how GTAs can spread genes — including those tied to antibiotic resistance.

17 Apr 2026
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