Randomized head-to-head TMS trial: medial prefrontal target produced larger anxiety drops than conventional DLPFC in comorbid depression

A phase 2 randomized trial (NCT04604210) found neuronavigated TMS to a dorsomedial prefrontal cortex target reduced anxiety more than a conventional left DLPFC target in patients with major depressive disorder and comorbid anxiety; both targets produced similar depression improvements.

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Duke-led simulations show skull‑conforming flexible ultrasound arrays sharpen subcortical tFUS targeting

A Duke University simulation study (npj Acoustics, 30 Mar 2026) finds skull‑conforming flexible ultrasound arrays can produce smaller foci, higher peak pressure and lower sidelobes than a semi‑spherical array for ~4 cm subcortical targets; results come from MRI‑derived head models and are computational only.

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Lantern-shaped ventricular BCI records stable deep-brain signals and decodes rat memory with 98% accuracy

A Tsinghua University team placed an expandable, lantern‑shaped electrode inside the lateral ventricle. In rats the ventricular BCI recorded stable signals for up to six months and decoded memory‑guided T‑maze choices with up to 98% accuracy.

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Whoop raises $575 million at $10.1 billion valuation

Whoop raised $575 million at a $10.1 billion valuation in a round led by Collaborative Fund, with participation from the Qatar Investment Authority and athletes LeBron James and Cristiano Ronaldo. The company makes a 24/7 wristband that tracks HRV, blood pressure and blood oxygen and has shifted from an elite-athlete focus toward broader consumer health.

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Market report projects closed-loop neuromodulation processors will reach $4.63 billion by 2030

The Business Research Company forecasts the closed-loop neuromodulation processor market will reach $4.63 billion by 2030 (12.9% CAGR), citing AI-driven adaptive processors, wearable controllers and telemedicine integration; the report also highlights Medtronic's Feb 2025 FDA approvals and a 2023 Amber–Bioinduction acquisition.

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Cortical beta rhythms encode motor and uncertainty signals; beta‑frequency rTMS shortens reaction time

A 2026 EEG‑rTMS study in 24 adults shows cortical beta oscillations separately encode uncertainty and movement preparation, and that beta‑frequency rTMS—especially when started at the beta trough—shortens reaction times and reduces beta desynchronisation.

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