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SOND exits stealth with $7M and debuts Dreambuds, a closed-loop sleep earbud

SOND, founded by Bose’s former Head of Sleep Yadid Ayzenberg, left stealth with $7M and launched Dreambuds, an in-ear closed-loop sleep system that tracks 12 physiologic signals and uses a cloud AI coach. The company plans mass production in Q2 2026 after a crowdfunding push and is taking reservations now.

28 May 2026

Meta-analysis of 21 studies links postherpetic neuralgia to network-level brain changes

A voxel-wise meta-analysis of 21 studies (31 datasets) finds that postherpetic neuralgia involves structural and resting-state functional changes across three brain systems—sensory association, affective–cognitive, and cortico‑basal ganglia—pointing to candidate biomarkers and neuromodulation targets but noting small, heterogeneous evidence and a need for longitudinal validation.

27 May 2026

Brainstem population activity traces an infraslow signal that predicts and gates REM sleep

Neuropixels recordings in mice show two dominant brainstem population components: a REM-activated signal and an infraslow component that predicts NREM→REM transitions up to ~110 seconds before onset. Optogenetic activation of medullary circuits modulated the infraslow component and changed REM induction.

27 May 2026

Adam Vareberg develops wireless scalp stimulators at UW–Madison

Adam Vareberg, a Harvard S.B. ’19 and Ph.D. student at UW–Madison’s Aviad Hai Lab, is developing wireless scalp stimulators designed to target brain regions without the implanted leads used in conventional deep brain stimulation.

27 May 2026

Machine learning optimizes dual-target DBS of subthalamic nucleus and substantia nigra

A 2026 npj Parkinson’s Disease paper presents a machine-learning pipeline that models and ranks dual-target DBS protocols for the STN and substantia nigra using imaging, electrophysiology and clinical-response data; results are computational and require clinical validation.

27 May 2026

Staged and simultaneous bilateral DBS show similar clinical outcomes; staged procedures consume more resources

A 2026 matched analysis of 504 patients found staged and simultaneous bilateral DBS produced similar surgical and clinical outcomes, but staged implantation required more anesthesia, operating-room time, and hospital days.

27 May 2026
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