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SCRATCH‑HTN pilot: ear‑based neuromodulation safe but misses primary endpoint; 12 mmHg signal in highest‑BP subgroup

At ACC 2026, investigators reported SCRATCH‑HTN pilot results: transcutaneous autonomic neuromodulation was safe and acceptable but did not beat sham overall; a subgroup with higher baseline systolic blood pressure showed about a 12 mmHg reduction. The randomized pilot enrolled 63 patients (2:1 randomization).

22 Apr 2026

Northwestern team prints artificial neurons that activate living mouse brain cells

Northwestern researchers printed flexible electronic neurons from MoS2 and graphene that generated complex spike patterns and activated neurons in mouse cerebellum slices, the team reports in Nature Nanotechnology. The paper frames the result as a step toward direct brain–device communication and more energy-efficient neuromorphic hardware.

22 Apr 2026

Japanese team launches open‑label pilot of Vielight PBM for cognitive impairment in schizophrenia

NCNP Tokyo has started a single‑arm 12‑week pilot trial of combined transcranial and intranasal photobiomodulation using the Vielight Neuro Gamma 4 in people with schizophrenia. The study (jRCTs032240756) will prioritize safety and tolerability and explore effects on cognition (MCCB), MMN and frontal NIRS.

22 Apr 2026

Review: Neuromodulation techniques relieve IBS symptoms, long-term benefit uncertain

A 21 April 2026 Frontiers review by Zhang et al. finds electroacupuncture, sacral nerve stimulation, taVNS and TENS can improve IBS symptoms but notes large patient-to-patient variability and limited long-term data.

22 Apr 2026

MRI-guided TMS reduces amygdala threat responses and improves PTSD symptoms

A randomized, blinded Emory trial found two weeks of MRI-guided low-frequency TMS reduced right amygdala threat responses and produced clinically meaningful PTSD symptom relief in 74% of treated participants, with benefits lasting at least six months.

21 Apr 2026

Pulsed taVNS elicits pupil dilation only with earlobe sham and short pulses, study finds

A Psychophysiology study (Apr 2026) finds pulsed taVNS produces pupil dilation in intermixed trials only with short (1.0 s) pulses and an earlobe sham; using a scapha sham or timing pulses to exhalation removed the effect, challenging a vagal-afferent mechanism.

21 Apr 2026
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